Download Autophagy, Infection, and the Immune Response by William T. Jackson,Michele Swanson PDF

By William T. Jackson,Michele Swanson

The courting among an infection and immunity and autophagy, a pathway of mobile homeostasis and pressure response, has been a quickly transforming into box of analysis over the past decade. whereas a few mobile strategies are seasoned- or anti-infection, autophagy has been confirmed to be either: part of the innate immune reaction opposed to a few microbes, and a mobile pathway subverted via a few pathogens to advertise their very own replication.

Autophagy, an infection, and the Immune Response provides a unified evaluation of the jobs of mobile autophagy in the course of microbial an infection. Introductory chapters ground the reader by way of delineating the autophagic pathway from a mobile perspective, and through directory assays to be had for measuring autophagy. next chapters address virus interactions with autophagy equipment, a few of the roles of autophagy parasitic an infection, and interactions of micro organism with the autophagic pathway. Concluding chapters explore the relationships of autophagy to systemic immune responses, together with antigen presentation, ER tension, and construction of IFN-gamma.

Designed as a source for these attracted to beginning studies on the connection among autophagy and an infection or immunity, Autophagy, an infection, and the Immune Response combines useful state-of the artwork method descriptions with an summary of the big variety of identified interactions among pathogens and the autophagic pathway.

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